United Kingdom
A young lady, Miss Mary Morstan, contact Sherlock Holmes for his help regarding her father, captain Morstan, who disappeared 10 years ago. Since his disappearance she annually receives a valuable pearl by post from an unknown person. The mystery leads Holmes and doctor Watson into an intricate plot regarding a lost treasure belonging to four convicts on the Andaman Islands. - IMDb
| I synomosia ton tessaron (transliterated title) |  Greece |
| A Négyek jele |  Hungary |
| Podpis čtyř |  Czechoslovakia |
| The Return of Sherlock Holmes: The Sign of Four (video box title) |  USA |
| Il segno dei Quattro |  Italy |
| Sherlock Holmes: De fyras tecken |  Sweden |
| Sherlock Holmes: Podpis štyroch |  Slovakia |
| Sherlock Holmes: The Sign of Four (DVD box title) | USA |
| Sherlock Holmes: Znamení čtyř | Czechoslovakia |
| Sherlock Holmes: Znamenie štyroch | Slovakia |
| The Sign of Four | United Kingdom |
| El Signo de los cuatro |  Spain |
| Znak czterech |  Poland |
| Σέρλοκ Χολμς: Το σημάδι των τεσσάρων | Greece |
| Знак четырех |  Soviet Union |
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Courtney Roper-Knight | Wiggins |
